The cytotoxicity of siRNA, VP16
, and RES was evaluated in cells grown in ML and SP using MTT (3-[4,5-diMethylThiazol-2-yl]-2,5-diphenylTetrazolium bromide) (Sigma, M5655).
We found good survival rates of KS patients in routine care, treated with ART and chemotherapy (ABV or oral VP16
) and/or radiotherapy for selected patients.
We also observed a difference between capillin and VP16
in terms of the relationship between the JNK and ERK signaling pathways.
is a topoisomerase II inhibitor commonly used in chemotherapy protocols for acute leukemia to induce the apoptosis of leukemic cells.
She received systemic chemotherapy with DDP, VP16
and Bleomycin (BLM) for two circles since latter.
The two most widely used treatment protocols in South Africa are the BFM-NHL and LMB protocols, which include a number of chemotherapeutic drugs (including prednisone, high-dose methotrexate, cyclophosphamide, vincristine, doxorubicin, cytarabine and VP16
) given precisely at specified times, consisting of a number of cycles depending on the stage of the disease as induction, consolidation and in certain instances maintenance therapy.
Phase II trial with etoposide (VP16
) plus ifosfamide plus high-dose cisplatin (VIhP regimen) in refractory germ cell tumour s.
The protein, called VP16
, acts as the gatekeeper for viral activity, new results in mice show.
A p53-independent Fas-mediated apoptosis in MCF-7 breast cancer cells in response to sodium butyrate was determined using the PFT-[alpha]  as well as the increased induction of genetic instability in lymphblastoma cells by etoposide (VP16
EXPRESSION OF CYCLIN B1 IN P53-MUTANT U138 MG GLIOBLASTOMA CELLS AFTER EXPOSURE TO ETOPOSIDE (VP16
To illustrate the practice of this invention, we have induced: (1) the intracellular aggregation of the cytoplasmic tail of the zeta chain of the T cell receptor (TCR)CD3 complex thereby leading to signaling and transcription of a reporter gene, (2) the homodimerization of the cytoplasmic tail of the Fas receptor thereby leading to cell-specific apoptosis (programmed cell death) and (3) the heterodimerization of a DNA-binding domain (Gal4) and a transcription-activation domain (VP16
Since the GFP-labeled protein, VP16
, is a tegument protein, the moving particles we observed must include at least tegument, either as whole virus, tegument plus capsid, or simply as tegument aggregates.