VVORVisually Enhanced Vestibulo-Ocular Reflex (laryngoscope studies)
VVORVisual Vestibulo Ocular Reflex
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Abbreviations CANVAS --cerebellar ataxia, neuropathy, vestibular areflexia syndrome VVOR --visually enhanced vestibulo-ocular reflex VOR --vestibulo-ocular reflex CABV --cerebellar ataxia and bilateral vestibulopathy VHIT --video head impulse test MRI --magnetic resonance imaging SCA3 --spinocerebellar ataxia type 3 FRDA --Friedreich ataxia The age of CANVAS onset is at the 60's, with a mean duration of symptoms of 11 years at the time of diagnosis [3, 4].
In patients with CANVAS, a highly characteristic clinical sign is positive VVOR test.
Positive VVOR test indicates simultaneous nonfunctioning smooth pursuit system and vestibuloocular reflex, which is the main clinical sign in patients with CANVAS [2].