VCAM1

(redirected from Vascular Cell Adhesion Molecule 1)
Also found in: Medical.
AcronymDefinition
VCAM1Vascular Cell Adhesion Molecule 1
References in periodicals archive ?
Concentration of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), E-selectin, P-selectin, urokinase plasminogen activator (uPA), plasminogen activator inhibitor 1 (PAI-1), endothelin-1 (ET-1), tissue factor pathway inhibitor (TFPI), growth-related oncogene 1 (GRO-1), transforming growth factor [beta]1 (TGF-[beta]1), tumor necrosis factor [alpha] (TNF[alpha]), and interleukin 6 (IL-6) in serum and/or in conditioned medium generated by endothelial cells was measured using appropriate DuoSet[R] Immunoassay Development kits (R&D Systems), according to manufacturer's instructions.
In turn, NF-[kappa]B activation results in the production and expression of chemotactic proteins, adhesion molecules such as selectins, integrins, intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), platelet/ endothelial cell adhesion molecule 1 (PECAM-1/CD31), and a host of cytokines and chemokines.
Many studies have supported the pathogenetic role of vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) in inflammation and response to injury (8, 9).