Although the mean values of WPT, CPT and WCPI for lesions of different aetiologies were statistically different from those obtained for the leprosy-lesions, overlap of the confidence intervals was observed in the leprosy group following stratification according to monofilament threshold (Table 1).
10[degrees]C) and 10 exhibited altered WPT, three showed normal CPT values ([greater than or equal to] 2895[degrees]C) and 12 exhibited altered CPT, but all 15 presented altered WCPI values (> 6.
2 g monofilament during the assay of leprosy skin lesions, and within this set three had normal WPT and 16 had altered WPT, three had normal CPT and 16 had altered CPT, but all 19 presented altered WCPI values.
The results derived from quantitative thermal testing show that WPT, CPT and WCPI values of leprosy skin lesions are typically increased compared with skin lesion of other aetiologies and SAWL.
The WPT, CPT and WCPI values of leprosy skin lesions in those patients who perceived the 0.
As the pressure thresholds increased, the mean values of WPT, CPT and WCPI increased linearly.
For individuals of the leprosy group, the minimum absolute difference between the WCPI of lesions and the WCPI of contralateral or ipsilateral SAWL was found to be 4.
The WCPI value, which embraces both WPT and CPT parameters, was the best indicator of thermal sensation, a term used in the literature as a non-specific expression that does not describe warm and cold stimuli explicitly in terms of units of temperature.
The large standard deviations obtained for WPT, CPT and WCPI in leprosy-diagnosed patients (as shown in Tables 1 and 2) indicate that the lesions investigated were of a heterogeneous nature, involving not only several clinical forms of the disease, but lesions of different evolution times (30 days to 60 months), many of which may not have been accurately reported by the patients themselves.
Patients presenting necrobiosis lipoidia, in which thermal sensation may be altered, (43) was not evaluated in the present study nor were comparisons WPT, CPT and WCPI with other diagnostic methods.
In conclusion, it has been established that cutaneous lesions in leprosy-diagnosed patients are characterized by alterations in thermosensation, functionally expressed as warm hypoaesthesia, or cold hypoaesthesia, or both, through the determination of WPT, CPT and WCPI values using the method of levels.
236 WCPI Mean [+ or -] standard deviation ([degrees]C) Tested skin area Non-leprosy Leprosy Suspected lesion 2.