This exciting three party research collaboration among world leaders in this field may increase the chance of translating basic scientific research in apoptosis, the process of programmed cell death, as carried out by our collaborators over recent years, into novel targeted cancer therapeutics," says Dr Julian Clark, Head of Business Development at WEHI.
We believe both will be excellent collaborators in bringing forward potential novel cancer therapeutics that target the apoptosis pathway," explains WEHI cancer researcher, Dr.
The IC 50 values for total extract and reference drug (the concentration that inhibits the invasion of the WEHI 164 cells by 50% relative to untreated control) were calculated as 15 and 46 [micro]g/ml, respectively.
In the invasive assay, the invasion of WEHI 164 cells was significantly inhibited at lower concentrations of the umbelliprenin and persicasulphide B.
In a modified procedure, fibroblast L929 cells were replaced by WEHI 164 cells of clone 13 (kindly provided by Prof.
This finding prompted the comparative study of TNF-sensibility in WEHI 164 and fibroblast L929 cells.
The new agreement provides an important expansion of the initial license agreement covering patent rights signed by Chemicon, Amrad and WEHI
This new agreement provides an important expansion of the initial license agreement covering LIF patent rights signed by Chemicon, Amrad and WEHI
in 1999 to include additional fields of use in non-therapeutic fields.