It is not a disease in itself, but it is an important risk factor for cardiovascular mortality and morbidity according to the seventh report of Joint National Committee (JNC) on prevention, detection, evaluation, and treatment of increased blood pressure (BP) (2003), and WHO-ISH
guidelines (2003) have defined it to be 140 mm Hg systolic and 90 mm Hg diastolic though risk appears to increase even above 120/80 mmHg.
2012) used Chinese Guidelines for the Management of Hypertension-2005 (CGMH-2005), 2 trials (Ge and Pan 2008; Guo and Chen 2013) used WHO-ISH
guidelines for the management of hypertension-1999 (WHO-ISH
GMH-1999), 1 trial used Practice of Internal Medicine (10th edition), and 2 trials (Chen 2011; Xu et al.