WML or WM hyperintensities are usually located around the ventricles, especially close to the ventricular horns.
Both the occurrence and the progression of WML are associated with cognitive decline, dementia, stroke, and mortality. A longitudinal cohort study conducted over 4 years by Uiterwijk et al . suggested that, in hyperintensive patients, the progression of periventricular WML was related to cognitive impairment (especially executive function), whereas there was no association between baseline periventricular WML and cognitive dysfunction.
Linear measures of cerebral atrophy, the number and topography of CMBs, WMLs
and lacunes were comparatively analyzed in patients with and without cognitive impairment.
Even subcortical ischemic vascular disease, including silent lacunar infarcts and WMLs
, may be associated with late-life depression, often referred as "vascular depression" .
, as a subtype of CVSD, are also called leukoaraiosis (LA) or white matter hyperintensities (WMHs).
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Objective: To find out the frequency of cerebral white matter lesions (WML
) in elderly individuals with no neurological symptoms.
White matter lesions (WMLs
) are characterized mainly by white matter hyperintensities on T2-weighted and fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) of the brain, and they are usually categorized into periventricular and subcortical lesions.
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Patients with migraine are at increased risk for white matter lesions (WMLs
) detected on magnetic resonance imaging (MRI) and these lesions are common, especially in females having migraine with aura (MA) (1).
"Regression of WMLs
in terms of number and size in the brain were observed after 1-2 years of supplementation.
Cerebral white matter lesion (WML
) on magnetic resonance imaging (MRI) is a common finding in the elderly, signifying chronic bilateral ischaemic brain injury .