The first T2D GWAS meta-analysis was published in 2008 and was also a European study , representing collaboration between three different consortia; the WTCCC
, DGI, and the Finland--United States Investigation of NIDDM Genetics (FUSION) which combined to form the Diabetes Genetics Replication and Meta-Analysis (DIAGRAM) consortium.
(66.) Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, et al., for the WTCCC
and the Cardiogenics Consortium.
Genome-wide association studies by the Wellcome Trust Case Control Consortium (WTCCC
) highlighted the association of SNP markers on chromosome 9p21.3 with coronary artery disease (6).
Similarly restricted genomic databases include the Genetic Association Information Network (GAIN) and the Wellcome Trust Case Control Consortium (WTCCC
Analyses by the Wellcome Trust Case Control Consortium (WTCCC
) for example, found a powerful association between chromosome 9p21.3 and coronary artery disease (CAD), an association not previously identified in other CAD studies.