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References in periodicals archive ?
A relatively distinctive feature of stacked G-quartets compared to Watson-Crick base paired structures is the presence of a coordination pocket that is often occupied by a variety of physiological cations such as [K.sup.+], N[H.sup.4+], [Ca.sup.2+], and [Na.sup.+] as well as others such as [Sr.sup.2+] and [Pb.sup.2+].
These nucleases can be broadly divided into two classes based on their mode of DNA recognition; ZFN, TALEN and meganucleases bind to DNA via protein-DNA interaction, whereas Cas9 binds to DNA with a short guide RNA (g RNA) by Watson-Crick base-pairing.
Yes, it's true; the four nitrogenous bases--adenine, guanine, thymine, and cytosine, which we learned as the inviolate structures at the basis of Watson-Crick pairing--aren't actually inviolate.
We found that m[s.sup.2] modification attenuates reverse transcription because it sterically hinders Watson-Crick base pairing.
Normally A binds with T and C binds with G called complementary base pairs, also referred to a Watson-Crick complementary.
By adapting nuclear magnetic resonance (NMR) technology, Al-Hashimi's group was able to observe transient, alternative forms in which some steps on the stairway come apart and reassemble into stable structures other than the typical Watson-Crick base pairs.
The term "RNA World" refers to a hypothetical time in the evolution of life on earth in which catalytic RNA was the sole genetic material and in which the standard Watson-Crick pairing was the basis of genetic manipulation; a hypothesis that has been given a new lease on life due to the recent discovery of present-day RNA molecules that do indeed display catalytic activity.
degree, and, in 1952, a Master''s degree in zoology from the University of Florida By 1959, experiments and analysis such as the Avery-MacLeod-McCarty experiment, the Hershey-Chase experiment, the Watson-Crick structure and the Meselson-Stahl experiment had shown DNA to be the molecule of genetic information.
This type of bonding follows "Watson-Crick Complementary", which says that base A only bonds with base T, base G only with base C, and vice versa.
From the earliest discoveries concerning nucleic acids and their biochemistry, through the Watson-Crick model of the DNA molecule and translation of genes into proteins, it was apparent that these genetic elements called genes were responsible for much of what went on in living cells.