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Related to Werner syndrome: progeria, ataxia telangiectasia
WRNWorld Radio Network
WRNWerner Syndrome
WRNWomen's Rights Network
WRNWomen's Rabbinic Network
WRNWavelength-Routed Network
WRNWideband Radio Networking
WRNWhite Rock Networks
WRNWind and Residual Noise
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References in periodicals archive ?
Oshima, "International registry of Werner syndrome," http://www.wernersyndrome.org/registry/registry .html.
Garcia-Gimonez et al., "Oxidative stress and antioxidant response in fibroblasts from Werner and Atypical Werner Syndromes," Aging, vol.
The disease is caused by a mutation to the Werner syndrome RecQ helicase-like gene, known as the WRN gene for short, which generates the WRN protein.
Much of the accelerated aging phenotype in Werner Syndrome is probably due to increased levels of the inflammatory cytokines produced by senescent cells.
When defective, they are linked to genetic diseases such as Bloom syndrome, which carries an increased risk of cancer, and Werner syndrome (premature aging).
Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors.
Werner syndrome, a genetic disorder also called adult progeria, leads to graying hair, cataracts, osteoporosis and other signs of aging in people in their 20s.
Few syndromes such as tibial hemimelia-foot polydactly triphalangeal thumbs syndrome (Werner syndrome), tibial hemimelia diplopodia syndrome, tibial hemimelia-split hand/foot syndrome, tibial hemimelia-micromelia-trigonobrachycephaly syndrome, tibial hemimelia-normal upper limb syndrome and tibial hemimelia-radial agenesis syndrome are considered to be transmitted as autosomal dominant.
Since its inception in 1998, Ellison's Medical Foundation has provided more than $300 million to fund basic biomedical research on aging relevant to understanding life span development processes and age-related diseases and disabilities, including stem cells, telomeres, longevity genes, DNA and mitochondrial damage, Werner Syndrome, Alzheimer's disease, neural development, degeneration and cognitive decline, and cellular response systems to aging and toxins.
The protein, WRNp, is the product of a gene associated with Werner syndrome, an autosomal recessive disorder hallmarked by premature aging.