Whole brain radiation
therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: Phase III results of the RTOG 9508 randomised trial.
In 2012, Yaginuma reports successful treatment of CNS PTLD with whole brain radiation
and discontinuation of immunosuppression therapy .
Studies suggest that stereotactic radiosurgery has better clinical outcomes than whole brain radiation
Aoyama and colleagues reported on a randomized trial of SRS plus whole brain radiation
therapy (WBRT) vs.
Cancer patients who receive stereotsctic radiosurgery (SRS) and whole brain radiation
therapy for the treatment of metastatic brain tumors have more than twice the risk of developing learning and memory problems than those treated with SRS alone, maintains research from the University of Texas M.D.
When the brain tumor has spread, two treatment options are advised, whole brain radiation
therapy and stereotactic radiosurgery (includes brain base knife package).
Studies have shown that lapatinib treatment after whole brain radiation
therapy can improve survival in patients with HER2-positive breast cancer with multiple brain metastasis with significant neurological symptoms (7).
Safety and feasibility of motexafin gadolinium administration with whole brain radiation
therapy and stereotactic radiosurgery boost in the treatment of </= 6 brain metastases: a multi-institutional phase II trial.