XIST


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AcronymDefinition
XISTXml Index Selection Tool
XISTX Inactive-Specific Transcript (genetics)
XISTCandidate Gene for X-Inactivation Center
References in periodicals archive ?
The Xist LncRNA exploits three-dimensional genome architecture to spread across the X chromosome.
The study suggests that over-production of XIST and genes from the inactive X chromosome are common denominators in the development of psychiatric disorders in patients with rare chromosome disorders, such as Klinefelter syndrome and Triple X syndrome, and in the general population of female psychiatric patients.
4] Nonstandard abbreviations: AKI, acute kidney injury; ICU, intensive care unit; RRT, renal replacement therapy; ncRNA, noncoding RNA; lncRNA, long ncRNA; AMI, acute myocardial infarction; eGFR, estimated glomerular filtration rate; MDRD, Modification of Diet in Renal Disease; CRP, C-reactive protein; SOFA, sequential organ failure assessment; APACHE II, Acute Physiology and Chronic Health Evaluation II; RIFLE, risk, injury, failure, loss of kidney function, and end-stage kidney disease; cel-miR-39, Caenorhabditis elegans microRNA 39; microRNA; AACt, threshold cycle; TapSAKI, TrAnscript Predicting Survival in AKI; AUC, area under the ROC curve; Xist, X-inactlve specific transcript.
Lawrence and her colleagues were able to accomplish this integration and overcome two major obstacles: the challenge of working with pluripotent stem cells, and inserting such a large amount of DNA (the XIST gene) via genomic editing.
Lawrence's team thought that if they added XIST to another chromosome, it might shut that one down too.
By inserting the XIST gene into a specific location in one copy of chromosome 21, they were able to deactivate it.
La asociacion del ARN de XIST en diversas secuencias a lo largo del futuro X inactivo, dispara una cascada de modificaciones epigeneticas que resultan en la formacion de heterocromatina facultativa (19).
Elan Corporation, plc is a neuroscience-focused biotechnology company, that brings innovations in science to fill significant unmet medical needs that continue to xist around the world.
Both long ncRNA molecules such as Xist and very short, microRNAs (miRNA) are discussed, but with specific disclaimers about how much is not yet known about their roles in gene expression or about their usefulness in treating cancer.
Aktif kalan X kromozomundaki XIST ise metillenmistir ve eksprese edilmez.
For example, miRNAs and a large set of ncRNAs including: Air, H19, Ipw, NTT, Tsix and XIST in mammals (known as "gene regulators") have been proposed to have different functions ranging from imprinting to inactivation of X-chromosome in mammals (17)
Editor's Note: This paper was originally published as XIST Technical Note 1636, Development and Demonstration of a Method to Evaluate Bio-Sampling Strategies Using Building Simulation and Sample Planning Software, June 2009.