XMRKXiphophorus Melanoma Receptor Kinase
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Primers were designed that anneal to the usually highly conserved exon sequences of tyrosine kinase proto-oncogenes (Xsrc, Xyes, Xmrk) and that reveal products spanning the more divergent intermittent introns (fig.
velifera digested with seven restriction enzymes and hybridized to the Xmrk and Xsrc probes revealed more than 120 informative fragments.
Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus.