XMuLVXenotropic Murine Leukemia Virus
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The titers for the other spiking viruses were 7.35, 5.30, and 7.70 for PRV, BVDV, and XMuLV respectively.
Filtration under targeted manufacturing conditions resulted in an average [greater than or equal to] 4.92 for PRV, 4.26 for XMuLV, 4.29 for BVDV, and 3.74 for BPV (Table 2, Figure 2).
Characterization of Model Viruses Used in Virus Validation Studies Virus Genome Enveloped Family BPV DNA No Parvo XMuLV RNA Yes Retro PRV DNA Yes Herpes BVDV RNA Yes Flavi Resistance to Physicochemical Virus Size (nm) Reagents BPV 20-25 High XMuLV 80-100 Low PRV 150-200 Medium BVDV 40-70 Medium BPV = bovine parvovirus; XMuLV = xenotropic murine leukemia virus; PRV = pseudorabies virus; BVDV = bovine viral diarrhea virus Table 2.