"Xenotropic Murine Leukemia Virus-related Virus (XMRV
)." The Centers for Disease Control and Prevention.
Gupta et al., "Detection of an infectious retrovirus, XMRV
, in blood cells of patients with chronic fatigue syndrome," Science, vol.
We have just finished the wild ride that was XMRV
. For those who missed it, a prominent retrovirologist, Judy Mikovits, published a very informative article on XMRV
in the October 2009 issue of Science.
They examined blood samples from 147 people diagnosed with chronic fatigue syndrome and 146 healthy subjects and found no evidence of either XMRV
or pMLV infection in either group.
In 2009, Science reported that two thirds of blood taken from individuals with the syndrome tested positive for the mouse leukemia virus XMRV
, compared with the meager 3.7 percent of samples taken from healthy controls.
Now, Jay Levy at the University of California, San Francisco, has drawn a blank when screening for XMRV
in 61 people with CFS, 43 of whom had tested positive in Lombardi's study.
But they found no evidence of XMRV
or any other mouse-related virus.
Therefore, we studied the presence of XMRV
and polytropic MLV-related retroviruses in a group of patients with fibromyalgia.
"I have Hep C, HIV, a new virus called XMRV
and one of the donors who I received blood from had CJD, and on top of that I have haemophilia.
In particular a retrovirus XMRV
, found by American researchers (Lombardi et al, Whittemore Peterson Institute, University of Nevada, October 2009) to be present in two-thirds of patients, compared with less than 4% in the healthy population.
Michael Busch, director of the Blood Systems Research Institute in San Francisco and a member of a federally funded group studying whether the retrovirus XMRV
, which some studies show linked to chronic fatigue syndrome, poses a threat to the blood supply told The Wall Street Journal, "We learned from HIV that we have to react aggressively to every next potential threat." (1)
Partial list of viruses and the year they were reported to be associated with MS (adapted from R Johnson, 1998) (33) Virus Years Rabies 1946, 1964 Herpes simplex 1964 Scrapie agent 1965 MS-associated agent 1962 Parainfluenza virus 1 1972 Measles 1972 Simian virus 5 1978 Chimpanzee cytomegalovirus 1979 Coronavirus 1980 SIMON-like virus 1982 Tick borne encephalitus flavivirus 1982 HTLV-1 1986 LM7 (retrovirus)--MSRV 1989, 1997 HSV-1 1989 MS1533 (retrovirus) 1994 HHV-6 1993, 1995 Borna virus 1998 EBV 1998, 2003, 2007 Varicella zoster 2004 XMRV