Y-MRSYoung Mania Rating Scale
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In the studies, the main outcome measure was the change from baseline in the Young Mania Rating Scale (Y-MRS).
The second monotherapy trial of 286 patients with manic or mixed episodes was conducted in India; patients were "extraordinarily ill" and had an entry Y-MRS of 39--about 10 points higher than usually seen in the United States.
They had "a terrific response," with an average 22.7-point drop in the Y-MRS scale, he said.