ZADDZentrale Abrechnungsstelle Darmstadt Dieburg (German: Darmstadt Dieburg Central Clearinghouse)
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Zadd represents the total additive dose of the drugs, theoretically providing a 30% reduction in the time of licking relative to the vehicle.
Isobolograms were built taking these data into account the obtained experimental [ED.sub.30] values (Zexp) of the combinations were less than the calculated theoretic determined ED30 values (Zadd).
Table 2 Theoretical (Zadd) and experimental (Zexp) [ED.sub.30] values for the combinations of the Rhodiolo rosea extract with the B vitamins and the interaction index values.