Our results showed that Gram-negative bacilli were least susceptible to amoxicillin-clavulanic acid
Gram-positive bacteria isolates showed a higher level of sensitivity to amoxicillin-clavulanic acid
(92.8%) followed by gentamycin (71.4%), but were resistant to tetracycline (71.4%) and nitrofurantoin (64.3%).
1.2 g 8 hourly and ceftriaxone 2 g once daily were prescribed for 2 weeks, with an excellent outcome.
We found that the UPEC strains had a higher level of resistance against aminopenicillins (ampicillin (85%) and amoxicillin (65%)) and a lower level of resistance against amoxicillin-clavulanic acid
It is alarming that the most commonly prescribed antibiotic of our OPD, amoxicillin-clavulanic acid
has developed a lot of resistance.
Ten to fourteen days of treatment with tigecycline, amoxicillin-clavulanic acid
, levofloxacin, and cefmetazole are recommended in the literature.
(14) Isolates were tested for their susceptibility against 15 antimicrobial agents including; amikacin (30 [micro]g), amoxicillin (10 [micro]g), amoxicillin-clavulanic acid
(30 [micro]g), ceftazidime (30 [micro]g), ceftriaxone (30 [micro]g), cefuroxime (30 [micro]g), chloramphenicol (30 [micro]g), ciprofloxacin (5 [micro]g), gentamicin (10 [micro]g), nalidixic acid (30 [micro]g), nitrofurantoin (50 [micro]g), ofloxacin (5 [micro]g), tetracycline (30 [micro]g), tobramicin (10 [micro]g) and trimethoprim-sulfamethoxazole (25 [micro]g), (Oxoid, England).
ESBL- producing strains were detected by the double-disk synergy test performed as a standardized disk diffusion assay in which an amoxicillin-clavulanic acid
disk was placed at the centre of a plate and ceftazidime, cefotaxime,ceftriaxone and aztreonam disks, 25 mm away (centre to centre) from the amoxicillin-clavulanic acid
Treatment of upper respiratory tract infection was also continued with orally administered amoxicillin-clavulanic acid
. His chest discomfort was relapsed in spite of the anti-anginal therapy regimen.
Moxifloxacin may be slightly more convenient, as it was given once daily for 5 days, versus twice daily for 7 days for amoxicillin-clavulanic acid
. Comparative costs will depend on the local market and availability of generics.
Thirty-five patients received appropriate treatment; 23 patients were given ceftazidime (2 g 3x/d for [greater than or equal to] 14 days) with or without SMX/TMP (30 mg/kg 2x/d), 6 received amoxicillin-clavulanic acid
(875-1,000 mg 3x/d) with or without SMX/TMP, and another 6 received SMX/TMP with doxycycline (200 mg 1x/d).
The antibacterial agents tested included cephalothin (30 [micro]g), cephalexin (10 [micro]g), ampicillin (30 [micro]g), cotimoxazole (30 [micro]g), streptomycin (30 [micro]g), amoxicillin-clavulanic acid
(30 [micro]g), nalidixic acid (30 [micro]g), pefloxacin (10 [micro]g), ofloxacin (10 [micro]g), ciprofloxacin (10 [micro]g) and gentamicin (10 [micro]g).