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Related to antithrombin: heparin, Antithrombin deficiency
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References in periodicals archive ?
2013) Novel prothrombin mutation in two families with prominent thrombophiliathe first cases of antithrombin resistance in a Caucasian population.
Table 2: Mean value of the Antithrombin III in stage 0 3 and 4 6.
AT III assay was performed by automated coagulation analyzer (Sysmex CA-1500) using INNOVANCE antithrombin kit (Siemens Healthcare Diagnostics products GmbH).
The assay of antithrombin is an important test in the identification of thrombotic factors because a partial deficiency of this protein is associated with a high risk of thrombotic disease.
With FDA approval of ATryn, we can help ensure that patients with hereditary antithrombin deficiency, a rare clotting disorder associated with severe complications, have access to much needed therapy," says Jeffrey Aronin, Ovation's president and CEO.
To mimic real clinical laboratory practice as much as possible, we used only lyophilized plasma from healthy volunteers or patients with antithrombin activity in the range of 400-1200 units/L for distribution within the surveys of the ECAT Foundation.
That statistically significant decline may not seem like a big change, but antithrombin III's anticoagulant function is probably tightly regulated within a narrow range, she said.
3) Heparin interference with the coagulation process is achieved by attaching to thrombin and antithrombin, by attaching to antithrombin alone, or by inhibiting platelets.
The furthest along, he estimates, is a milk-produced blood-clotting agent, antithrombin III, developed by Genzyme Transgenics Corp.
Antithrombin iii inf the subject of the public contract is continuous deliveries of infusion containing the active substance antithrombin iii for 2 years.
Alnylam Pharmaceuticals, a United States-based biopharmaceutical company, has commenced a Phase I open-label extension (OLE) trial with ALN-AT3, a subcutaneously administered, investigational RNAi therapeutic, targeting antithrombin, it was reported on Friday.