On day 16 after the patient was admitted to the hospital, results of laboratory testing showed improved values for creatine phosphokinase (1,855 ng/mL), aspartate aminotransferase
(101 IU/L), alanine aminotransferase (162 IU/L), lactate dehydrogenase (294 IU/L), and urine myoglobulin (10 [micro]g/L).
Damaged muscle cells release creatine kinase (MM isoform), myoglobin, and aspartate aminotransferase
, as well as lesser amounts of alanine aminotransferase and lactate dehydrogenase.
Serum iron, total iron binding capacity (TIBC), percentage saturation, body weight, albumin, aspartate aminotransferase
, and hematocrit were monitored at regular intervals for 2.
8%, platelet count 21,000 cells/[micro]L, aspartate aminotransferase
107 U/L (7-40 U/L) alanine aminotransferase 56 U/L (550 U/L), alkaline phosphatase 164 U/L (40-150 U/L), and serum creatinine 3.
Results of the 18,000-patient Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET) demonstrated that less than 1% of patients had elevations of the liver enzymes aspartate aminotransferase
and alanine aminotransferase greater than three times the upper limit of normal, "which is similar to levels observed with currently available NSAIDs," the company noted.
Results of the 18,000-patient Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET) showed that less than 1% of patients had elevations of the liver enzymes aspartate aminotransferase
and alanine aminotransferase greater than three times the upper limit of normal, "which is similar to levels observed with available NSAIDs," Novartis noted, adding there were no cases of jaundice or hepatic failure with lumiracoxib 100-mg once-daily dosing in the clinical development program, it.
8 percent), aspartate aminotransferase
(AST) elevation (3.
found to produce different results when the PTS was used (potassium, lactate dehydrogenase, aspartate aminotransferase
, phosphate), on the basis of the allowed relative deviation of QCs as specified by the German Federal Medical Council (2).
0 Aspartate aminotransferase
, IU 167 Alanine aminotransferase, IU 139 Alkaline phosphatase, IU 80 Proteinuria, mg/dL + CSF cytology Lymphocytes, 54 cells/[mm.
and alanine aminotransferase levels greater than 60 U/L were seen in 15%.