demonstrated retrospectively on a large cohort of CSU patients how high values are associated with urticarial activity, life impairment, autologous serum skin test
, and arterial hypertension .
Clinical and Investigative assessment of patients with positive versus negative autologous serum skin test
: a study of 80 South Indian patients.
These antibodies are involved in the pathogenesis by activating mast cells or basophils leading to histamine release.2,3 When autologous serum is injected intradermally in these patients, an immediate wheal and flare reaction is observed and this forms the basis for autologous serum skin test
(ASST), a simple screening test to identify these patients.4
Macchia et al., "Infiltrating cells and related cytokines in lesional skin of patients with chronic idiopathic urticaria and positive autologous serum skin test
," Experimental Dermatology, vol.
In this study in Group 1, out of 113 patients (100%) 74 patients (65.48%) were Autologous Serum Skin Test
positive and 39 patients (34.52%) were Autologous Serum Skin Test
Greaves, "The autologous serum skin test
: a screening test for autoantibodies in chronic idiopathic urticaria," British Journal of Dermatology, vol.
It has been observed that autologous plasma, anticoagulated with substances other than heparin, generates positive autoreactive responses in a higher percentage of patients than autologous serum skin test
(ASST) [62, 63].
The autologous serum skin test
(ASST), performed by intradermal injection of autologous serum using careful sterile technique, is rarely used in practice.
Clinicoepidemiologic features of chronic urticaria in patients having positive verses negative autologous serum skin test
: a study of 100 Indian patients.
A positive autologous serum skin test
(ASST) result confirms a diagnosis of autoimmune urticaria, although a negative ASST finding does not rule out an autoimmune etiology.
Autologous serum skin test
autologous plasma skin test autoimmune chronic urticaria.