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BOTOXBotulinum Toxin
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Botulinum toxin type a for control of drooling in Asian patients with cerebral palsy.
The researchers found that, based on the 14 patients who completed the study, the visual analogue scale score and scar width measurements showed a significant improvement in appearance and narrower scars for the halves of the scars treated with botulinum toxin type A (P = 0.046 and 0.001, respectively).
Its lead product candidate is an injectable 900 kDa purified botulinum toxin type A complex.
faecium genome, the lab's computer programs quickly spotted the genetic sequence for the novel botulinum toxin.
Botulinum toxin is synthesized by Gram-positive anaerobic bacterium Clostridium botulinum (6, 8, 9), and inhibits the release of acetylcholine at the neuromuscular junction, preventing muscle contraction.
One of them is the injection of botulinum toxin type A, and the other one is the respective surgery of the masseter muscle and angulus of the mandible.
Botulinum toxin reaches the cholinergic nerve terminal, exhibiting typical selectivity when injected into a target tissue.
Due to its effect of blocking the action of acetylcholine at neuromuscular junction, botulinum toxin A is very helpful in relieving muscle spasms.
A total dose of 6.5 units of botulinum toxin A (1.5, two, and three units into three sites from lateral to medial) was injected intramuscularly into the right part of the frontal muscle.
This will be the first ever attempt to introduce a self-developed botulinum toxin to the US market by a South Korean company.