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References in periodicals archive ?
Carbon tetrachloride administration in rats for 24 h is known to induce marked increase in serum ASAT and ALAT activities, primed liver lipid peroxidation, depleted sulfhydryl contents, impaired total antioxidant capabilities and induced genotoxicity.
Assay method for antihepatotoxic activity using carbon tetrachloride induced cytotoxicity in primary cultured hepatocytes.
Effects of kefir on liver weights and total body weights of mice treated with carbon tetrachloride (C[Cl.sub.4]) at the end of study (4 weeks) Treatment Groups Liver weight /100g body weight Control 1.1070 (n= 10) [+ or -] 0.04842 Kefir 1.1190 (n=10) [+ or -] 0.04656 CCl4 1.9900 (n= 5) [+ or -] 0.13565 (a,b) Combination 1.3900 (n= 5) [+ or -] 0.08741 (a,b,c) Total 1.3103 (n=30) [+ or -] 0.06545 Treatment Groups Body weight (% of initials) Control 27.2000 (n= 10) [+ or -] 0.48419 Kefir 27.3100(n=10) [+ or -] 0.58356 CCl4 22.3000 (n= 5) [+ or -] 0.96954 (a,b) Combination 24.4000 (n= 5) [+ or -] 0.87178 (a,b,c) Total 25.9533 (n=30) [+ or -] 0.47766 Data are presented as mean [+ or -] standard error of 10 animals/group.
The analysis of glutathione concentrations (Figure 1(b)) showed that the levels of the reduced and the oxidized forms did not significantly differ between the control and supplemented group (reduced glutathione: control = 15.9 [+ or -] 1.06; supplemented = 16.6 [+ or -] 1.06 nmol/mg protein; oxidized glutathione, control = 1.25 [+ or -] 0.079; supplemented 1.22 [+ or -] 0.030 nmol/mg protein; in the carbon tetrachloride control group, values were increased (p < 0.050) compared with the control and supplemented groups (reduced glutathione = 10.0 [+ or -] 0.75 nmol/mg protein; oxidized glutathione = 7.52 [+ or -] 1.20 nmol/mg protein); the oxidative stress index was calculated using the ratio between reduced glutathione/oxidized glutathione).
Syrup injection before and after exposure to carbon tetrachloride has a protective effect, which manifests itself in preventing partial involution lymphoid organs, reducing by half the number of hemorrhages and ulcerations in the gastric mucosa.
Molecular process in acute liver injury and regeneration induced by carbon tetrachloride. Life Sci.
Simsek et al., "Protective effect of Panax ginseng against serum biochemical changes and apoptosis in liver of rats treated with carbon tetrachloride (C[Cl.sub.4])," Journal of Hazardous Materials, vol.
Abstract: Repeated chromatographic separation and purification of pet-ether and carbon tetrachloride soluble fractions of a methanol extract of stem bark of Mesua nagassarium (Burm.
Physical and chemical characteristics of the shell surrounding the metallic iron core are likely to play an important role in determining the chemical reaction pathway taken place during the breakdown of carbon tetrachloride (CT).