Also found in: Medical.
CHKLChong Hwa Kuala Lumpur (school; Kuala Lumpur, Malaysia)
CHKLCity Hall Kuala Lumpur (Malaysia)
Copyright 1988-2018, All rights reserved.
References in periodicals archive ?
PSO induced DNA damage and increased protein expression of [gamma]-[H.sub.2]AX, phosphorylation of ATM, ATR, Chkl, and Chk2.
Further experiments revealed that oxidative stress in sperm activated G2/M delay by cascade of ATM [right arrow] Chkl [right arrow] Cdc25B/Cdc25C to repair damaged DNA [19-21].
In chromosome 9, one of these "hot spots" contained two genes that are known to be involved in cancer: the tumor suppressor gene ATM and the gene for Chkl, which functions in the repair of damaged DNA (Hunter et al.
PTEN silence showed no effect on the lengths of comet tails (Figure 9(a)) and pATM expression but significantly decreased p-Chk1 expression in response to Cuc B (Figure 9(b)), while silence ATM dramatically inhibited Cuc B-induced phosphorylation of both PTEN and Chkl (Figure 9(c)).
* Associated with increased ATM, Chkl, and Chk2 phosphorylation and reduced cdc25C levels.