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With the more sensitive RNA-DNA hybridization, RIA, and counterimmunoelectrophoresis assays, nanogram amounts of circulating DNA can be quantified (19, 63, 64).
These methods may be 1,000 times more sensitive than counterimmunoelectrophoresis (CIE) and immunodiffusion (ID) tests that require precipitin reactions between antibodies and tissue/cell extracts.
Also, detection of Hib polysaccharide antigen by latex agglutination (LA), counterimmunoelectrophoresis (CIE), polymerase chain reaction (PCR) of CSF, serum, or urine can aid in diagnosis.
pneumoniae as the cause of death; pneumococcal infection was confirmed by polymerase chain reaction (PCR), using primers for the pneumococcal autolysin gene on autopsy tissue, and by counterimmunoelectrophoresis (CIE) of CSF (serogroup 19).
For the rapid identification of capsular type, counterimmunoelectrophoresis is an important diagnostic tool.
Comparison of enzyme immunoassay, counterimmunoelectrophoresis and polyacrylamide gel electrophoresis for the diagnosis of rotaviruses.
Other immunodiffusion assays, such as counterimmunoelectrophoresis (5) and radioimmunoprecipitation (13,14), are more rapid tests with lower detection limits than the precipitation technique.