Table 2: Expression of renal cyclooxygenases
(COX-1 and -2) in rats with PUUO at 9 and 15 weeks (mean ± SEM) [Table omitted]
This is the first report of the cyclooxygenase
inhibitory activities of dihydrokawain, demethoxyangonin, flavokawain A, kawain, dihydromethysticin, yangonin and methysticin isolated from kava kava roots.
and ten alkamides from various Achillea species were examined for cyclooxygenase
and 5-lipoxygenase activities (Muller-Jackic et al.
isozymes: the biology of prostaglandin synthesis and inhibition.
regulates angiogenesis induced by colon cancer cells.
Zingarelli B, Southan GI, Gilad E, O'Connor M, Salzman AL, Szabo C (1997) The inhibitory effects of mercaptoalkylguanidines on cyclooxygenase
For antioxidant and cyclooxygenase
inhibitory assays, test compounds were prepared in DMSO and were tested at varying concentrations ranging from 50-250 [micro]g [ml.
2] 0/11 22/39 15/15 iNOS 0/11 20/39 15/15 MHC class II 0/11 20/39 15/15 (*) HCNA indicates histologically classified normal appendices; COX-2, cyclooxygenase
The way NSAIDs inhibit the formation of prostaglandins is by inhibiting their precursor enzymes, cyclooxygenase
The Lipomics platform enables users to profile a broad range of eicosanoids in the cyclooxygenase
, lipoxygenase and P450 pathways.
In the cyclooxygenase
(COX) enzyme inhibitory assay, the red sweet cherry water extracts inhibited the enzymes by 80 to 95% at 250 microg/mL.
This effect was inhibited by indomethacin (10 [micro]M) and ZM230487 (1 [micro]M), selective inhibitors of cyclooxygenase
and of 5-lipoxygenase, respectively.