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References in periodicals archive ?
There have been only five reported cases of concordant DS in dizygotic twins with confirmed chromosomal analyses [2, 6, 13].
Meda War, "The use of skin grafting to distinguish between monozygotic and dizygotic twin in cattle," Heredity, vol.
Median, Confidence Interval (CI), Intrapair Variance of Displacement Speed (VDS) and Partial Correlations Controlling for Age (r), Height, Body Mass, Displacement Speed (DS) and the Heritability of: (a) Monozygotic and Dizygotic Twins of Both Sexes; (b) Female Monozygotic and Dizygotic Twins; and (c) and Male Monozygotic and Dizygotic Twins.
For the new study, the researchers recruited 78 monozygotic-twin pairs and 27 pairs of dizygotic twins from the registry.
This assay allows the genotyping of 15 multiple informative genetic markers (CSF1PO, D2S1338, D3S1358, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, D5S51, FGA, TH01, TPOX, VWF, and AMELXloci), which allows for the identification of monozygotic and dizygotic twins [23].
Also, those women undergoing in vitro fertilisation and other fertility treatments have a higher risk of having twins, that are dizygotic, monozygotic or identical, or other multiples.
It is more commonly seen in monozygotic twins as compared to dizygotic twins and singletons, the reported incidence being 100-150 times higher.
In addition, the reported 63% concordance rate among monozygotic twins compared to the null concordance among dizygotic pairs [6], scoring as the highest among autoimmune diseases [5], indicated that gene susceptibility played an important role in the pathogenesis of PBC.
We note how de novo mutations may also help explain why the concordance rate for autism is so markedly higher in monozygotic than dizygotic twins.
(1) In addition to being matched on typical characteristics such as age or race, twins are by design matched in varying degrees on genetic propensity: monozygotic (MZ) twins share 100% of their genetic makeup and dizygotic (DZ) twins share on average 50%.
The studies conducted by McGuffin and Reich on monozygotic and dizygotic twins suggest genetic predisposition because high concordance rate was found in monozygotic with absence in dizygotics and more prevalence in first degree relatives of OCD than in population at large.