VP-16

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Related to etoposide: cisplatin, Ifosfamide
AcronymDefinition
VP-16Etoposide
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References in periodicals archive ?
Randomized trial of Etoposide and Cisplatinversus Etoposide and Carboplatin in Patients with Good-Risk Germ Cell Tumors.
Our patient was initially treated according to HLH-2004 guidelines with etoposide and high-dose steroids.
After interim response assessment, cycles 3 and 4 consisted of VIP (etoposide 100 mg/[m.sup.2], ifosfamide 2000 mg/[m.sup.2], and cisplatin 30 mg/[m.sup.2] on days 1-3 also in a three-weekly cycle).
As expected, when we evaluated the chemosensitivity of CSC from HeLa SP, we found that they were highly resistant to Etoposide (VP16) as compared to the same cells, but grown as monolayer (Figures 1(a)-1(c)).
In the case of high risk of development of pulmonary hemorrhage, the VIP regimen (etoposide, mesna, ifosfamide, and cisplatin) could be chosen as first-line CT.
The genotoxic drugs cisplatin (DNA binder), etoposide (topoisomerase II inhibitor), irinotecan, and topotecan (topoisomerase I inhibitors) were used to treat in vitro the following NB cell lines: SKN-AS, SH-SY5Y, SH-EP, SK-N-SH, SK-N-BE(2)c, LA-N-5, and IMR-32.
In a retrospective study at IU [7], 184 consecutive patients with testicular or retroperitoneal primary GCT underwent two cycles of high-dose carboplatin and etoposide, each followed by ASCT.
The two essential databases of medical literature, Medline/PubMed and Embase were searched for articles related to oral etoposide in advanced breast cancer.
Although no consensus guidelines exist for treating endometrial YSTs, most patients in the literature underwent cytoreductive surgery, usually followed by a regimen of bleomycin, etoposide, and cisplatin as first-line adjuvant treatment.
At the American Society of Clinical Oncology 2017 Genitourinary Cancers Symposium, researchers presented the results of a single-arm trial investigating the efficacy of a single cycle of bleomycin, etoposide, and cisplatin (BEP) as adjuvant chemotherapy for high-risk, stage 1, non-seminomatous or combined germ cell tumours of the testis (NSGCTT).