fCJDFamilial Creutzfeldt-Jakob Disease
References in periodicals archive ?
fCJD is caused by the inherited E200K point mutation, where the amino acid glutamic acid is replaced by lysine at position 200.
If codon 178 encodes for a valine, then the mutation will result in fCJD.
In humans the most common TSEs are sporadic, familial, and variant Creutzfeldt-Jakob disease (sCJD, fCJD, and vCJD, respectively).