GJIC

(redirected from gap junctional intercellular communication)
AcronymDefinition
GJICgap junctional intercellular communication
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Effective reduction of neuronal death by inhibiting gap junctional intercellular communication in a rodent model of global transient cerebral ischemia.
The effects of carbenoxolone, a semisynthetic derivative of glycyrrhizinic acid, on peripheral and central ischemia-reperfusion injuries in the skeletal muscle and hippocampus of rats
Assay Biological functions represented Induction of cytochrome P450 enzymes Receptor-mediated activity (Ah receptor) Activation of mitogen-activated protein kinases Intracellular signaling Disruption of gap junctional intercellular communication Intercellular signaling, cell death Activation of AP-1 transcription factor Gene expression Alteration in neutrophil function Cellular function, cell death Stimulation of insulin release Cellular function Contraction of uterine muscle in vitro Integrated tissue function Alteration in fertilization in vitro Integrated tissue/organ system function Stimulation of lymphocyte Proliferation, cell death proliferation Table 2.
An approach to evaluation of the effect of bioremediation on biological activity of environmental contaminants: dechlorination of polychlorinated biphenyls
The SAR models for eye irritation (47), sensory irritation (48), developmental toxicity in humans (49) and in hamsters (50), allergic contact dermatitis (51), inhibition of gap junctional intercellular communication (GJIC) (52), and environmental biodegradation (53) were also used.
Estimating the extent of the health hazard posed by high-production volume chemicals. (Articles)
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