Three case reports published between 2002 and 2010 describe generalized tonic-clonic seizures
secondary to quetiapine use.
The epilepsy patients further divided into five subgroups: patients suffering from seizures predominantly Generalized Tonic-Clonic Seizures
, Complex Partial Seizures, Simple Partial Seizures, Absence Seizures and Unknown/unclassified.
Disrupted Connectivity within the Thalamocortical Network during Generalized Tonic-Clonic Seizure
. Synchronization (i.e., events occurring at the same time) in epilepsy is conceptually complex, and both decreases and increases in synchrony have been reported with ictogenesis .
All the cases suffered from generalized tonic-clonic seizures
Based on data accumulated to date, the sNDA also seeks to potentially expand the pediatric indication to include children 2 years of age and older for the treatment of primary generalized tonic-clonic seizures
The product, which received 510(k) clearance from the Food and Drug Administration in January, detects patterns in motion and physiological signals that may be associated with generalized tonic-clonic seizures
, and immediately alerts caregivers.
The unidentified teen was first taken to the emergency room of a hospital due to generalized tonic-clonic seizures
, according to a case study released by The New England Journal of Medicine on Thursday.
Diaphoresis, hyperthermia, hypertension, tachycardia, and tachypnea are more uniquely associated with PSH, while unusual ocular and oral movements, cyanosis, salivation, desaturations, and pupillary dilation characterized by a postictal period are more commonly associated with seizures, particularly generalized tonic-clonic seizures
Levetiracetam Injection is an antiepileptic drug indicated for adjunct therapy in adults (more than 16 years of age) with the following seizure types when oral administration is temporarily not feasible: Partial onset seizures, Myoclonic seizures in patients with juvenile myoclonic epilepsy, Primary generalized tonic-clonic seizures
Cardiac dysrhythmias are commonly seen with seizures, especially generalized tonic-clonic seizures
Cohort 1 will include 20 patients with primary generalized tonic-clonic seizures
. Cohort 2 will consist of 20 patients with partial onset seizures, including complex partial seizures with or without secondary generalization.
Roughly 6,530 hours of data were recorded over 272 days, including 40 generalized tonic-clonic seizures
. Embrace's algorithm was shown to detect 100 percent of the seizures.