hOCT1

AcronymDefinition
hOCT1Human Organic Cation Transporter-1
References in periodicals archive ?
Jorgensen et al., "The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia," Blood, vol.
Inui, "Decreased function of genetic variants, Pro283Leu and Arg287Gly, in human organic cation transporter hOCT1," Drug Metabolism and Pharmacokinetics, vol.
Examples are increased expression of the P-glycoprotein (Pgp) efflux pump, reduced expression of the organic cation transporter hOCT1, and sequestration of imatinib in the plasma by the serum protein acid glycoprotein (AGP) [40,41].