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Related to hereditary spherocytosis: Hereditary elliptocytosis
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References in periodicals archive ?
Mohandas, "Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders," Blood reviews, vol.
An adult with aplastic crisis induced by human parvovirus B19 as an initial presentation of hereditary spherocytosis. Korean J Intern Med.
(6.) Bader-Meunier B, Gauthier F, Archambaud F et al: Long term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis. Blood 2001; 97:399-403
Partial versus total splenectomy in children with hereditary spherocytosis. Surgery 2013;154(4):853-855.
High frequency of de novo mutations in ankyrin gene (ANK1) in children with hereditary spherocytosis. J Pediatr 1998; 132: 117-20.
UGT1 promoter polymorphism accounts for increased neonatal appearance of hereditary spherocytosis [Letter].
INTRODUCTION: Extramedullary hematopoiesis (EMH) is a common compensatory mechanism for chronic anemia found in patients with hemoglobinopathies such as thalassemia, sickle cell anemia, and hereditary spherocytosis. These patients are usually asymptomatic.
Achieve sensitive detection of red cell abnormalities without expensive and time-consuming manual tests, and differentiate microcytic anemias (thalassemia, iron deficiency) and macrocytic anemias (hereditary spherocytosis, sickle cell) with the RBC and reticulocyte technology.
Splenectomy plays a very important role in children with thalassemia, hereditary spherocytosis and chronic Idiopathic thrombocytopenic purpura recalcitrant to medical treatment.
(65) experimentally showed that PV-B19 significantly inhibited erythroid (CFU-E), myeloid (CFU-myeloid) and megakaryocytic (CFU-Mgk) growth in a patient with hereditary spherocytosis. PV-B19-infected patients seem to infer hematological findings as related with their own body physiology and response to virus toxicity.
A: The Dacie method for the deter mination of osmotic fragility has been the definitive method for the diagnosis of hereditary spherocytosis (HS) for quite some time, but as you point out, it is labor-intensive and also technically demanding.
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