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References in periodicals archive ?
In November 2017, the patient underwent skin biopsy that showed leukocytoclastic vasculitis and negative staining for Congo red and [kappa]-light chain (Figure 2).
Leukocytoclastic vasculitis may be idiopathic or associated with drugs, infections, malignancies, and connective tissue disorders.
Histologically, leukocytoclastic vasculitis of small vessels is present.
Leukocytoclastic vasculitis was not seen and the PAS staining was negative.
Although acute hepatitis A virus (HAV) infection is usually self-limiting, it may be rarely accompanied by extrahepatic manifestations such as evanescent rash, leukocytoclastic vasculitis, arthritis, glomerulonephritis, pleural effusion, ascites, cryoglobulinemia, autoimmune hemolytic anemia, and thrombocytopenia (1-3).
Leukocytoclastic vasculitis is an inflammatory disease of small vessels, also known as hypersensitivity vasculitis or hypersensitivity angutis.
The patient fulfilled the diagnostic criteria for Sweet Syndrome, including the two major criteria (abrupt onset of painful erythematous plagues and histopathologic evidence of a dense neutrophilic infiltrate without evidence of leukocytoclastic vasculitis).
The most common manifestations of this disease include leukocytoclastic vasculitis with palpable purpura and petechiae, arthralgias, renal disease, neurologic disease, and hypocomplementemia.
Skin biopsy from patients with the disorder is categorized as a neutrophilic urticarial dermatosis with histopathology demonstrating perivascular and interstitial neutrophilic inflammation with leukocytoclasia but without leukocytoclastic vasculitis [2, 5].
Leukocytoclastic vasculitis is the most common vasculitis associated with myeloproliferative disorders.
Her skin biopsy revealed leukocytoclastic vasculitis with few perivascular eosinophilic infiltrates, without granuloma, and her renal biopsy revealed mild interstitial inflammation.
Keywords: Vasculitis, cutaneous leukocytoclastic vasculitis.