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Related to matrix Gla protein: Osteocalcin, protein S
MGLAPMatrix Gla Protein
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Matrix GLA protein modulates differentiation induced by bone morphogenetic protein-2 in C3H10T1/2 cells.
Nazarian et al., "Vitamin K-dependent carboxylation of matrix Gla protein influences the risk of calciphylaxis," Journal of the American Society of Nephrology, vol.
Vitamin K inhibits vascular calcification by matrix GLa proteins. These proteins are activated via vitamin-dependent carboxylation.
Circulating nonphosphorylated carboxylated matrix gla protein predicts survival in ESRD.
Abbreviations MGP: Matrix Gla protein SDS: Sodium dodecyl sulfate PAGE: Polyacrylamide gel electrophoresis kDA: Kilodaltons.
Matrix GLA Protein + Vitamin K2 = Barrier against calcium infiltration
Matrix Gla protein (MGP) is expressed by chondrocytes and vascular smooth muscle cells to inhibit soft tissue calcification.
Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone.
In arteries, vitamin K2 activates a protein called matrix Gla protein. When matrix Gla protein is activated by vitamin K2, it prevents calcium from being deposited in arteries.
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