nPNANormalized Protein Nitrogen Appearance (nutrition)
nPNANexon Publishing North America
nPNANormal Park Neighborhood Association (Ypsilanti, MI)
nPNANon-Protein Nitrogen Appearance
nPNANormalized Protein N Appearance (biochemistry)
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Interestingly, our patients maintained adequate nutrition (mean serum albumin 3.9 g/ dL), despite the relatively low bicarbonate and low nPNA. Considering that the functioning of biological machinery is mainly influenced by changes in ([H.sup.+]), not (HC[O.sub.3.sup.-]), we wondered if the maintenance of serum pH well within a safe range at every studied point along the week could in part account for these findings.
Finally, it should be commented that the low nPNA of our patients might have contributed to the stability of the serum bicarbonate until 20 h post-dialysis.
There were no significant differences between the two groups with respect to PD time, Hb, baseline ALB, and baseline nPNA ( P > 0.05).
Screening with univariate Cox analysis, possible risk factors contributing to mortality were age, higher peritoneal transport status, ALB, Hb, HbA1c, TCcr, RRF, and nPNA. However, after multivariate Cox proportional hazards model analysis, mortality was independently predicted by advanced age, anemia, hypoalbuminemia, and lower RRF, but not higher peritoneal transport status [Table 4].{Table 3}{Table 4}
An alternative approach is to estimate TRU over a 7-day period, which corresponds to the urea generated within the same time period for the anuric patients, and calculate nPNA without blood sampling [4].
A good correlation between UV-absorbance and a small removed waste solute such as urea enables the determination of Kt V for urea [12], and nPNA [13].
PNA expresses total nitrogen appearance in terms of protein in grams per day and can be normalized to grams per kilogram per day (nPNA).
nPNA can be a good marker of protein intake if used in conjunction with other biochemical markers, and stated intake/diaries.
Normalise or stabilise biochemical markers, such as a Level III-2 (4) normalised protein appearance (nPNA) [greater than or equal to]0.8 g/day in haemodialysis.
In Table 10, hemoglobin A1c (p = .048) and the nutritional variables nPNA (p = .03) and albumin (p = .018) show a statistically significant relationship with history of foot ulcer and, in the case of hemoglobin A1c, with amputation (p = .048).
Protein-energy nutritional status should be evaluated using various measures, such as serum albumin, percent standard (NHANES II) body weight or subjective global assessment (SGA), normalized protein equivalent of total nitrogen appearance (nPNA), or by dietary interviews and diaries.