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Related to pharmacogenetics: Pharmacogenomics
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References in periodicals archive ?
The system is a highly sensitive, cost-effective, mass spectrometry-based platform for high-throughput genetic analysis, and is used globally in diverse research fields such as cancer profiling for solid tumors and liquid biopsies, inherited genetic disease testing, pharmacogenetics, agricultural genomics, and clinical research.
Guidelines and recommendations for laboratory analysis and application of pharmacogenetics to clin ical practice.
TPMT gene polymorphisms are pharmacogenetic markers which enable the individualization of thiopurine drug therapy.
Pharmacogenetics has enormous potential to improve the effectiveness and safety of the treatment patients receive and this post will make a major contribution to both boosting research capacity and raising awareness of pharmacogenetics among NHS clinicians.
This initiative will further emphasize development of the PharmGKB knowledge base; it is envisioned as an information resource that will be useful to the entire pharmacogenetics research community to enable future hypothesis-driven research.
In the 1950s, Arno Motulsky first conceptualized and investigated the effect of inheritance on individual drug response, leading to a large and growing body of work now known as pharmacogenetics and only recently beginning to reach critical mass.
FIRST TRIES One of the first widely used applications of pharmacogenetics is within the arena of cancer treatment.
This change of the science of genetics has also much affected pharmacogenetics.
Pharmacogenetics is the use of a patient's genetic information to inform the selection or dosing of medications.
A group of researchers from North America and Europe working in pharmacokinetics, biotechnology, pharmaceutical sciences, biochemistry, and gene expression, as well as gastroenterology and hepatology, provide a review of the historical discoveries and current development of nuclear hormone receptors as transcriptional regulators and the implications of this regulation in drug metabolism, development, clinical drug use, therapeutic potentials, and pharmacogenetics.
These early discoveries have evolved into our current understanding of pharmacogenetics as a complex trait.