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References in periodicals archive ?
Pei et al., "Comparison of single daily dose of methimazole and propylthiouracil in the treatment of Graves' hyperthyroidism," Clinical Endocrinology, vol.
Pires de Carvalho, "Thyroid [Ca.sup.2+]/NADPH-dependent H2O2 generation is partially inhibited by propylthiouracil and methimazole," European Journal of Biochemistry, vol.
Considering that a series of malformations occur with use of methimazole in pregnancy, propylthiouracil should be preferred in the first trimester (19).
Our patient's medications were changed to propylthiouracil 150 mg every 8 hours and propranolol 10 mg twice a day until a euthyroid state was achieved and she could tolerate a general anesthetic with out precipitating a thyroid storm.
The complementary list includes Lugol's iodine, potassium iodide, and propylthiouracil (2).
Carbimazole and propylthiouracil are examples of commonly used anti-thyroid drugs that are effective in reducing the production of thyroid hormones.
Newborn rats were assigned to groups of 6 rats each for subcutaneous (sc) injection of 0.5, 1.0, 1.5, 2.0, 4.0, or 50.0 [micro]g/100 g body weight (BW) triiodothyronine ([T.sub.3]; Sigma, USA; Hyper-5 group), groups of 12 rats each for sc injection of 5 or 10 mg/100 g BW propylthiouracil (PTU; Sigma; Hypo-5 group), or saline (0.9% NaCl; Control-5 group), for 5 days beginning on P1.
Therapeutically, D1 is inhibited by propylthiouracil, which is used to treat hyperthyroidism.
Hyperthyroidism is a common endocrine disorder and is mainly treated with anti-thyroid medications like propylthiouracil (PTU) and carbimazole.
Supertasters are defined by whether they can detect the presence of two bitter-tasting compounds, phenylthiocarbamide (PTC) and propylthiouracil (PROP), and geneticists have shown that this ability depends to a large extent on certain variations of a gene known as TAS2R38.
His liver functions improved and after 10 days, we started propylthiouracil. He has been on it for three months and his liver function tests were normal.
Results of some derivatives of 2-thiouracil, such as propylthiouracil, which was used as antithyroid drug, produced thyroid cancers in human and in some animals such as mice, rats, and hamsters [5].