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References in periodicals archive ?
Miyamato et al, showed that MIA induced osteoarthritic knee models in rats and rabbits exhibited chondrocyte death and loss of proteoglycan which progressed to cartilage destruction, subchondral bone exposure and functional impairment similar to humans13.
Caption: An image of the proteoglycans that have increased in the perineuronal net (green) that surrounds nerve cells (red) in the spinal cord following injury.
Mammalian expression of full-length bovine aggrecan and link protein: formation of recombinant proteoglycan aggregates and analysis of proteolytic cleavage by ADAMTS-4 and MMP-13.
The ECM receptor glypican-LP (CGI_10016108) is a major heparan sulfate proteoglycan and together with syndecan-LP (CGI_10004071) is highly expressed from the early stages until the early trochophore stage.
Proteoglycan components of the intervertebral disc and cartilage endplate: An immunolocalization study of animal and human tissues.
Hardingham, "The role of link-protein in the structure of cartilage proteoglycan aggregates," Biochemical Journal, vol.
Therefore, we can only speculate that similar pathways involved in ECM proteoglycan remodelling could affect UTI biosynthesis in the liver.
The correlation of AP-1 with type II collagen, proteoglycan, Cytokeratin 8 protein, MAP-1, MAP-2, and MAP-4 and the correlation of AP-1 with IL-1[beta], TNF-[alpha], IL-6, IL-8, MIP-1, MCP-1, and NO were detected.
Zhang et al., "Reprogramming of human fibroblasts into multipotent cells with a single ECM proteoglycan, fibromodulin," Biomaterials, vol.
ECM proteins such as the heparan sulfate proteoglycan (HSPG) agrin have been associated with senile plaques (SPs) and neurofibrillary tangles (NFTs) [86, 87].
After blocking with 5% skim milk, the membranes were incubated with rabbit anti-rat chondroitin sulfate proteoglycan, key raw tenascin C, type IV collagen (1:1000; Bioss Inc.), and GAPDH (1:10000; Bioss Inc.) primary antibodies at 4[degrees]C overnight.
The chrondroitin sulfate proteoglycan (CSPG4) regulates human trophoblast function.