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References in periodicals archive ?
Proteoglycan components of the intervertebral disc and cartilage endplate: An immunolocalization study of animal and human tissues.
Caption: Figure 2--Photomicrographs of the joint cartilage of mice after the experimental induction of OA in DMM: A, E), group treated with AuNP-PAH; A: slight unevenness of the joint surface (arrow) with disorganization of the chondrocyte columns; B, F) group treated with curcumin; C, G) group treated with AuNP-PAH-curcumin; C) Integrity of the joint surface can be seen despite the slight disorganization of chondrocyte columns and cluster formation (arrow); D, H) control group treated with saline solution; D) Intense fibrocartilage formation, disorganization, and bone remodelling; H) intense decrease in proteoglycans shown by the decrease in Safranin O/Fast Green staining.
Notably that the chondroitin sulfate proteoglycans (CSPGs) such as versican accumulate in tumor stroma and play a key role in tumor growth and invasion.
Most sulfated GAG chains are components of proteoglycans (PGs) where are they covalently linked to core protein.
Olczyk, "Influence of proteolytic-antiproteolytic enzymes and prooxidative-antioxidative factors on proteoglycan alterations in children with juvenile idiopathic arthritis," Clinical Biochemistry, vol.
doses of proteoglycan (PG) (50 [micro]g or 100 [micro]g) every three days.
2) The cartilage tissue of the patients with osteoarthritis and rheumatoid arthritis include biglycan fragments obtained due to breakdown of proteoglycans by ADAMTSs.
Further research showed that the specific gene affected was the gene for perlecan, which is a heparin sulfate proteoglycan, the major proteoglycan of basement membranes.
In healthy tissue, proteoglycans are important components in the matrix between cells and play a key role in maintaining the structure of the nervous system.
Notochord cells regulate intervertebral disc chondrocyte proteoglycan production and cell proliferation.
Evaluation of the intracellular function and basic structural properties of proteoglycan adhesion proteins and structural proteins may reveal new approaches to the treatment of pulmonary disease.
The Safranin O staining showed a significantly different proteoglycan profile between the CON group and the injury groups.