rhBSSLRecombinant human Bile Salt-Stimulated Lipase
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Kiobrina is a recombinant produced human bile-salt stimulated lipase (rhBSSL) developed by Sobi to improve growth in preterm infants who receive pasteurised breast milk or infant formula.
The company said that the phase III study is a multicenter, double- blind, placebo-controlled study where preterm infants younger than 32 weeks of gestational age are randomised to receive rhBSSL or placebo added to preterm formula or pasteurised human milk for four weeks to demonstrate improved growth velocity.
Kiobrina is a recombinant human bile-salt-stimulated lipase (rhBSSL) that restores the natural lipase activity level that is either lost during pasteurisation or totally absent in formula.