rt-PARecombinant Tissue Plasminogen Activator
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However, most scholars in China and abroad are devoted to the study of efficacy of single application of rt-PA intravenous thrombolysis and mild hypothermia treatment, but rarely reported the effect of rt-PA intravenous thrombolysis in combination with mild hypothermia treatment.
After the 2-hour administration of rt-PA, pulmonary arterial pressure is reduced by a mean of 30%, and cardiac index increases by 15% [18].
6) devoted to the care and management of AIS patients receiving rt-PA. Eight articles addressed the issues related to stroke treatment with rt-PA: pathophysiology, identification in triage, Code Stroke in the emergency department, dosing, monitoring, blood pressure control, management of complications, changes in community emergency response systems (EMS), development of care pathways, algorithms, and acute stroke orders after the administration of rt-PA.
According to the results of The National Institute of Neurological Disorders and Stroke (NINDS) study group, at least 30% of patients treated with IV rt-PA continue their lives with a mild deficit or no deficit after three months (5).
Clinical deterioration following improvement in the NINDS rt-PA Stroke Trial.
Patients were classified into IV rt-PA group or EVT (including IV rt-PA bridging EVT) group according to their recanalization treatment methods, and they were also divided into END or non-END subgroup according to their early neurological status.
The patient was given an intravenous infusion of 24 ml rt-PA (low dose) in 100 ml normal saline in 48 h (slow infusion time) twice.
Veno-occlusive disease (VOD) of the liver in Korean patients following allogeneic bone marrow transplantation (BMT): efficacy of recombinant human tissue plasminogen activator (rt-PA) treatment.
Abbreviations: ANOVA, analysis-of-variance; AQP4, aquaporin-4; BBB, blood-brain barrier; EB, Evans blue; MCAO, middle cerebral artery occlusion; OD, optical density; PCR, polymerase chain reaction; rt-PA, recombinant tissue plasminogen activator.