Ursoniu et al., "The impact of statin therapy on plasma levels of von Willebrand factor antigen
. Systematic review and meta-analysis of randomised placebo-controlled trials," Thrombosis and Haemostasis, vol.
On follow-up after a month on prednisone, his aPTT was 34.9, factor VIII activity was 114%, von Willebrand factor antigen
was 95%, and vWF:ristocetin cofactor assay was 81%.
Seven cryosupernatant samples were serially diluted twofold, and the VWF: Ag levels in the samples (neat) were measured by immunoturbidimetric assay using Hemosil von Willebrand Factor Antigen kit (Instrumentation Laboratory, Italy).
Cappelletti et al., "Validation of a rapid test (VWF-LIA) for the quantitative determination of von Willebrand factor antigen in type 1 von Wiilebrand disease diagnosis within the European multicenter study MCMDM1VWD," Thrombosis Research, vol.
prolonged bleeding after superficial lacerations 13 16 Female Epistaxis, 54.50 12.00 years prolonged bleeding alter superficial lacerations, prolonged bleeding alter tooth extraction 14 17 Male Epistaxis 77)90 23.00 years Patients Col/Epi(s) Col/ADP(s) 1 205 170 2 120 86 3 152 98 4 177 84 5 143 63 6 105 84 7 101 76 8 156 109 9 229 134 10 134 96 11 131 75 12 136 89 13 234 119 14 135 80 Col/ADP: collagen/adenosine diphosphate, Col/Epi: collagen/ epinephrine, vWF:Ag: von Willebrand factor antigen
, vWF:RCo: ristocetin cofactor activity.
 Nonstandard abbreviations: VWD, von Willebrand disease; PT, prothrombin time; aPTT, activated partial thromboplastin time; VWF:Ag, von Willebrand factor antigen
level; VWF:RCo, von Willebrand factor ristocetin cofactor activity; HMW, high molecular weight; IMW, intermediate molecular weight; LMW, low molecular weight; CBC, complete blood count; PT-VWD, platelet-type VWD; LD-RIPA, low-dose ristocetin-induced platelet aggregation.
Contract awarded for Von willebrand factor antigen
, reagent for the determination
ABBREVIATIONS: ELISA = Enzyme Linked Immuno-sorbent Assay; EQA = external quality assurance; LIA = Latex Immuno-Assay; LLS = Lower limit of sensitivity; QAP = Quality Assurance Program; VWD = von Willebrand disease; VWF = von Willebrand Factor; VWF:Act = von Willebrand Factor Activity' (assay); VWF:Ag = von Willebrand Factor Antigen
(assay); VWF:CB = von Willebrand Factor collagen binding (assay); VWF:RCo = von Willebrand Factor Ristocetin Cofactor (assay).
In this case, the initial VWD testing panel identified significantly decreased plasma von Willebrand factor ristocetin cofactor activity (VWF:RCo), with a discordantly low ratio of VWF:RCo to von Willebrand factor antigen
level (VWF:Ag) and normal coagulation factor VIII activity, suggesting types 2A, 2B, or 2M VWD (or acquired von Willebrand syndrome).
Because factor VIII reductions can be associated with impaired protection by its carrier protein, von Willebrand factor, it is advisable to quantitatively measure the von Willebrand factor antigen
and test for the functional von Willebrand factor ristocetin cofactor.
Von Willebrand factor antigen
by STA analyzers [Package Insert].